Parkinson's Disease
The gene therapy invented for Canavan Disease forms the backbone for current gene therapy trials happening with Parkinson's Disease. Though these trials are still in their infancy, gene therapy thus far with Parkinson's patients has shown an improved quality of life, improved movement, and a reduction in tremors. 

"Gene Therapy For Parkinson's Disease yields promising results in first patients" 

As we make further and further advancements into better targeting Canavan Disease through gene therapy, we will be able to advance in targeting and treating Parkinson's Disease as well. The ability to stop the atrophy in the brain of the most recent gene therapy is particularly promising, as it gives hope that the degenerative process in Alzheimer's and Parkinson's could also be stopped. 

Our research is truly on the cutting edge of modern medicine, and with your support, this research may one day make a difference in the life of someone you love.

Research Publications
The following is a list of Dr. Paola Leone's research publications relating to Alzheimer's and Parkinson's Disease:

During MJ, Leone P. Targets for gene therapy of Parkinson's disease: growth factors, signal transduction, and promoters. Exp Neurol, 144(1): 74-81, Mar 1997. Review.

Leone P, McPhee SW, Janson CG, Davidson BL, Freese A, During MJ. Multi-site partitioned delivery of human tyrosine hydroxylase gene with phenotypic recovery in Parkinsonian rats. Neuroreport, 11(6): 1145-51, Apr 2000.

Zaroff S, Leone P, Markov V, Francis JS. Transcriptional regulation of N-acetylaspartate metabolism in the 5xFAD model of Alzheimer's disease: Evidence for neuron-glia communication during energetic crisis. Mol Cell Neurosci, 65: 143-152, March 2015.